The Perricone MD High Potency Retinol Recovery Overnight Moisturizer works overnight with three forms of retinol to help support the skin’s natural recovery and renewal process, promoting a visible reduction in lines and wrinkles. It delivers intense hydration to thoroughly replenish and protect the skin’s moisture barrier for a visibly firmer and smoother complexion.Clinical Results:100% showed significant improvement in skin hydration**93% showed significant improvement in skin hydration for 12 hours*93% showed significant improvement in skin barrier function for 12 hours*80% showed significant improvement in skin brightness and radiance**Significant improvement in skin texture, tone and elasticity***In a clinical study of 30 women.**In a clinical study of 30 women after 8 weeks.